Willem-Jan Metsemakers Selected Research

Antibiotic Prophylaxis

6/2022	Correction to: Perioperative antibiotic prophylaxis in long bone open fractures: the need for randomized controlled trials.
2/2022	Duration of Perioperative Antibiotic Prophylaxis in Open Fractures: A Systematic Review and Critical Appraisal.
1/2022	Ninety-Day Follow-up Is Inadequate for Diagnosis of Fracture-related Infections in Patients with Open Fractures.
1/2022	Perioperative antibiotic prophylaxis in long bone open fractures: the need for randomized controlled trials.
2/2021	Impact of duration of perioperative antibiotic prophylaxis on development of fracture-related infection in open fractures.
5/2020	Local Application of a Gentamicin-Loaded Hydrogel Early After Injury Is Superior to Perioperative Systemic Prophylaxis in a Rabbit Open Fracture Model.
1/2018	Antibiotic Prophylaxis With Cefuroxime: Influence of Duration on Infection Rate With Staphylococcus aureus in a Contaminated Open Fracture Model.
10/2016	Injectable gentamicin-loaded thermo-responsive hyaluronic acid derivative prevents infection in a rabbit model.

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Willem-Jan Metsemakers Research Topics

Disease

25	Infections 05/2022 - 07/2015
8	Open Fractures (Compound Fracture) 06/2022 - 10/2016
5	Wounds and Injuries (Trauma) 01/2021 - 10/2016
2	Bacterial Infections (Bacterial Infection) 05/2022 - 01/2022
2	Osteomyelitis 03/2022 - 07/2015
2	Rupture 01/2022 - 10/2018
1	Prosthesis-Related Infections 05/2022
1	Hypersensitivity (Allergy) 05/2022
1	Superinfection 12/2021
1	Communicable Diseases (Infectious Diseases) 11/2021
1	Persistent Infection 01/2021
1	Surgical Wound 01/2021
1	COVID-19 01/2021
1	Coinfection 01/2021
1	Reinfection 01/2020
1	Pain (Aches) 12/2019
1	Humeral Fractures 12/2019
1	Tibial Fractures (Fracture, Tibial) 09/2017

Drug/Important Bio-Agent (IBA)

11	Anti-Bacterial Agents (Antibiotics)IBA 05/2022 - 07/2015
3	HydrogelsIBA 12/2021 - 10/2016
2	Gentamicins (Gentamicin)FDA LinkGeneric 05/2020 - 10/2016
2	Cefuroxime (Zinacef)FDA LinkGeneric 05/2020 - 01/2018
1	Vancomycin FDA LinkGeneric 05/2022
1	Clindamycin (Cleocin)FDA LinkGeneric 05/2022
1	Pharmaceutical PreparationsIBA 05/2022
1	beta-LactamsIBA 05/2022
1	isavuconazoleIBA 03/2022
1	Neutralizing AntibodiesIBA 12/2021
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2021
1	Bone Cements (Bone Glue)IBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 12/2019
1	Biocompatible Materials (Biomaterials)IBA 10/2016
1	Hyaluronic Acid (Hyaluronan)IBA 10/2016
1	AlloysIBA 07/2015
1	LipidsIBA 07/2015
1	PolymersIBA 07/2015
1	Doxycycline (Periostat)FDA LinkGeneric 07/2015
1	TitaniumIBA 07/2015

Therapy/Procedure

8	Antibiotic Prophylaxis 06/2022 - 10/2016
8	Fracture Fixation 01/2021 - 10/2016
5	Therapeutics 05/2022 - 01/2020
4	Phage Therapy 01/2022 - 01/2019
3	Debridement 01/2020 - 10/2018
2	Arthroplasty 11/2021 - 01/2021
2	Operative Surgical Procedures 10/2021 - 05/2020
1	Aftercare (After-Treatment) 01/2022
1	Knee Replacement Arthroplasty (Total Knee Replacement) 11/2021
1	Surgical Amputation (Amputations) 02/2021
1	Orthopedic Procedures 01/2021
1	Negative-Pressure Wound Therapy 01/2021
1	Time-to-Treatment 05/2020
1	Analgesia 12/2019
1	Length of Stay 09/2017
1	Injections 10/2016